Group equivariant non-expansive operators (GENEOs) are mathematical tools for approximating data observers when data are represented by real-valued or vector-valued functions (https://rdcu.be/bP6HV, https://www.nature.com/articles/s41598-025-90152-7). These operators focus on the assumption that data interpretation depends on the observers' geometric properties. In this talk, we will show how GENEOs can be used to locate pockets in proteins.